The Division of Bioinformatics and Biostatistics (DBB) develops integrated bioinformatics and biostatistics capability such as Artificial Intelligence (AI) and Machine Learning (ML), molecular modeling, real world data analytics, and chemoinformatics to address increasing needs of FDA in the areas of drug safety, drug repositioning, biomarker development, precision medicine, genomics, rare diseases, endocrine disruptors, and risk assessment.
Equipment:
- Illumina I-Scan System (Model I-Scan) – Methylation arrays, Human, Plant and Animal genotyping arrays
- Applied Biosystems DNA Sequencer (Model ABI 3730) – Capillary electrophoresis instrument for processing large numbers of sequencing or fragment analysis samples
- Illumina I-Scan Tecan Infinium Automation (Model SC-30-401) – Enables automation of sample preparation in the workflow
- Roche 454 DNA Sequencer (Model 454 GS Junior) – The next-generation GS Junior Sequencing System affords a comprehensive profiling of all the relevant genes and is known for producing quality long read sequences
- Applied Biosystems 7900HT Fast Real-Time PCR System (Model 4329001) – The 7900HT Fast Real-Time PCR System is a real-time quantitative PCR system that combines 96- and 384-well plate compatibility and the TaqMan Low Density Array with fully automated robotic loading
All potential use of NCTR equipment must be aligned with NCTR’s mission and may require a technology transfer agreement:
NCTR conducts scientific research to generate data for FDA decision making, and develops and supports innovative tools and approaches that FDA uses to protect and promote individual and public health.