Genetic Models Core

The Genetic Models Core provides state-of-the-art services to create novel genetically modified mice and cell lines. This core was created by expanding an existing transgenic mouse facility at UAMS, which has a strong record of producing transgenic mice. An important new addition is the use of the CRISPR-Cas system to provide gene-editing services in both mice and cell lines. This expansion of services establishes a Genetic Models Core that, in addition to meeting the needs of the COBRE Project Leaders, provides new cutting-edge services to the research communities at UAMS, ACRI, CAVHS, and across Arkansas.  The Genetic Models Core also provides maintenance services, including sperm cryopreservation, in vitro fertilization, and strain rederivation, all of which support the long-term needs of Project Leaders and other Center members.

If you’re interested in accessing this facility, you may qualify for a voucher to cover facility costs. Visit Research Vouchers – Arkansas INBRE to check your project’s eligibility.