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Arkansas Integrative Metabolic Research Center

The Arkansas Integrative Metabolic Research Center (AIMRC) is an NIH-designated Center of Biomedical Research Excellence (COBRE) established in April 2021 at the University of Arkansas with Phase I funding from NIGMS (P20GM139768).

 

If you’re interested in accessing this facility, you may qualify for a voucher to cover facility costs. Visit Research Vouchers – Arkansas INBRE to check your project’s eligibility.

Bioenergetics Core Equipment

    • Seahorse Pro Xfe96
    • Seahorse Xfe24
    • Seahorse Mini
    • BioTek Cell Imager
    • Oroboros O2k-FluoRespirometer
    • Spark Multimode Plate Reader
    • Optima™ MAX-XP Tabletop Ultracentrifuge
    • Promethion metabolic Cage
    • Sable Drosophila metabolic Cage with circadian rhythm monitor
    • Agilent LC MS qToF mass spectrometer

Data Science Core Equipment

    • Eighteen single A100 GPU dual CPU servers for DART.
    • Nineteen single V100 GPU dual CPU servers and about 400 non-GPU dual CPU servers.
    • Three Petabytes of DNN Lustre parallel storage, four PB of nearline Lustre and object storage, and InfiniBand and Ethernet networks to act as a single system.
    • 450 application packages installed from source or commercial sources, about 150 packages installed as Python or R modules, and hundreds of packages installed as RPMs (system packages) from CentOS, EPEL, and OpenHPC.
    • An OpenOnDemand web portal, Jupter Notebooks, RStudio, and other graphical interfaces in addition to command line batch computing.
    • Operating system: Ubuntu 20.04 + Lambda Stack
    • Software: TensorFlow, PyTorch, Caffe, Keras, CUDA, cuDNN
    • Two Dell PowerVault ME5084 Storage Arrays provide all AIMRC cores and member labs with high-speed access to data storage. There is 508TB of usable storage available to the center and its members, which is backed up daily to a separate server located off of the main campus. The platform is scalable and can be adapted to the evolving data storage needs of the center.

Imaging and Spectroscopy Core

The Imaging and Spectroscopy core is primarily located at the Engineering Research Center (ENRC) with a satellite facility available on campus adjacent to the Bioenergetics Core. These facilities currently occupy an area of over 3,000 sq. ft.
    • Bruker Ultima Investigator upright multiphoton microscope
    • Bruker Ultima Investigator inverted I multiphoton microscope
    • Horiba Confocal Raman microscope
    • Olympus Fluoview FV10i-LIV Confocal microscope
    • JY Horiba Imaging spectrometer
    • Andor Raman spectrometer
    • Ocean Optics UV-Vis-NIR FLAME spectrometers
    • Label-free multiphoton microscopy of NADH and FAD autofluorescence for in vivo or in vitro assessments of cell metabolism
    • Diffuse optical spectroscopy for in vivo studies of tissue oxygenation
    • Standard laser scanning confocal microscopy for live cell and tissue imaging
    • High-resolution Raman microscopy of biological tissue, cells, and materials