NCTR, Division of Systems Biology

National Center for Toxicological Research

Contact
Facility Contact Form orDr. Jessica Hawes,
Dr. Richard Beger (email)

The National Center for Toxicological Research (NCTR) is the primary research center of the U.S. Food and Drug Administration. The one-million square foot research campus in Jefferson, Arkansas plays a critical role in the missions of FDA and the Department of Health and Human Services to promote and protect public health.

Equipment:

Primary Contact – Dr. Jessica Hawes, NCTRResearch@fda.hhs.gov
https://www.https://www.fda.gov/about-fda/science-research-nctr/jessica-hawes

  • Agilent Seahorse XFe96 – measures the oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) of live cells in a 96-well plate format
  • Protein Simple—Wes – Simple Western size-based assays: Immunoassay and Total Protein assay
  • Protein Simple—Ella – Automated immunoassay testing within a microfluidic Simple Plex™ cartridge
  • Axion Maestro Pro – multiwell microelectrode array (MEA)
  • Agilent ePacer – easy and effective way to produce functionally mature hiPSC cardiomyocytes

Primary Contact – Dr. Richard Beger, Richard.Beger@fda.hhs.gov
https://www.fda.gov/about-fda/science-research-nctr/richard-beger

  • Bruker ScimaX FTMS  – high resolution mass spectrometer used for sample tissue imaging based on chemical composition
  • Bruker ultrafleXtreme MALDI TOF/TOF Mass Spectrometer – chemical composition and tissue imaging
  • Bruker 600 MHz NMR – Nuclear Magnetic Resonance Spectrometer system used for determining chemical composition of biofluids and tissue extracts
  • Thermo Orbitap Elite MS with Waters nanoflow UPLC – Liquid Chromatography Mass Spectrometry system used for analysis of proteins and peptides in tissues and biofluids
  • Thermo Orbitrap Exploris 240 Mass Spectrometer – Used for determining drug and metabolite composition of biofluids and tissue extracts
  • Waters TQ-XS MS – Liquid Chromatography Mass Spectrometry instrument for determining drug and metabolite composition of biofluids and tissue extracts

All potential use of NCTR equipment must be aligned with NCTR’s mission and may require a technology transfer agreement:

NCTR conducts scientific research to generate data for FDA decision making, and develops and supports innovative tools and approaches that FDA uses to protect and promote individual and public health.

If you would like to contact this core facility, please fill out the "Facility Contact Form" on the right of this page. This contact method helps ARA measure the success of the CFE in connecting potential collaborators and will flow directly to the core director’s email inbox.